abstract：PURPOSE:To investigate the association of cardiovascular risk factors and inflammatory markers with neovascular age-related macular degeneration (AMD). DESIGN:Cross-sectional case-control study. PARTICIPANTS:Of the 410 of the >/=65-year-old community sample invited to attend, 205 participated (50% response rate). Of ...

journal_title：Ophthalmology

authors： Hogg RE,Woodside JV,Gilchrist SE,Graydon R,Fletcher AE,Chan W,Knox A,Cartmill B,Chakravarthy U

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:En bloc perfluorodissection (EBPD) is a surgical dissection technique that facilitates removal of epiretinal membranes and the posterior hyaloid. It is carried out by injecting perfluorocarbon liquid between the retina and the posterior hyaloid to separate the epiretinal tissues from the subjacent retina. The...

journal_title：Ophthalmology

authors： Arevalo JF

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:To determine the intraocular pressure (IOP) profile during and after systemic dexamethasone treatment in preterm very low birth weight (VLBW; <1500 g) infants. DESIGN:A cohort study at a university-affiliated tertiary neonatal center. PARTICIPANTS:Twenty-seven VLBW infants who received a 3-week dose-tapering ...

journal_title：Ophthalmology

authors： Ng PC,Lee CH,Tam BS,Wong SP,Lam HS,Kwok AK,Fok TF

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To test if improving optical coherence tomography (OCT) resolution and scanning speed improves the visualization of glaucomatous structural changes as compared with conventional OCT. DESIGN:Prospective observational case series. PARTICIPANTS:Healthy and glaucomatous subjects in various stages of disease. MET...

journal_title：Ophthalmology

authors： Mumcuoglu T,Wollstein G,Wojtkowski M,Kagemann L,Ishikawa H,Gabriele ML,Srinivasan V,Fujimoto JG,Duker JS,Schuman JS

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To test a linear model relating the regional loss in retinal nerve fiber (RNFL) thickness to the corresponding regional loss in sensitivity with data from patients with previous anterior ischemic optic neuropathy (AION). DESIGN:Case-control study. PARTICIPANTS:Twenty-four individuals with AION and 20 with nor...

journal_title：Ophthalmology

authors： Hood DC,Anderson S,Rouleau J,Wenick AS,Grover LK,Behrens MM,Odel JG,Lee AG,Kardon RH

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence and risk factors of primary open-angle glaucoma (POAG) in an urban population and compare the same with that of our published rural population data in southern India. DESIGN:Population-based cross-sectional study. PARTICIPANTS:Four thousand eight hundred subjects 40 years or older...

journal_title：Ophthalmology

authors： Vijaya L,George R,Baskaran M,Arvind H,Raju P,Ramesh SV,Kumaramanickavel G,McCarty C

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To report endothelial cell densities (ECDs) and their correlation to anterior chamber depth (ACD) after implantation of the Artisan intraocular phakic lens. DESIGN:Prospective observational case series. PARTICIPANTS:Three hundred eighteen eyes of 173 myopic patients treated with the Artisan iris-fixated pha...

journal_title：Ophthalmology

authors： Saxena R,Boekhoorn SS,Mulder PG,Noordzij B,van Rij G,Luyten GP

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To investigate vitreous levels of reactive oxygen species (ROS) in patients with proliferative diabetic retinopathy (PDR) and analyze ROS levels among different groups of PDR patients. DESIGN:Retrospective case-control study. PARTICIPANTS:Thirty-nine eyes of 39 patients with PDR and 16 eyes of 16 non-PDR pa...

journal_title：Ophthalmology

authors： Yeh PT,Yang CM,Huang JS,Chien CT,Yang CH,Chiang YH,Shih YF

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:To investigate the association between seatbelt use and (1) the spectrum of ocular injuries and (2) visual acuity outcomes after motor vehicle accidents (MVAs) with airbag deployment. DESIGN:Single-center retrospective observational case series. PARTICIPANTS:Forty-seven patients involved in MVAs with airbag d...

journal_title：Ophthalmology

authors： Rao SK,Greenberg PB,Filippopoulos T,Scott IU,Katsoulakis NP,Enzer YR

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To document the long-term experience with hydroxyapatite (HA) orbital implants (Bio-Eye) and analyze the factors influencing implant exposure, including surgical type, procedural modification, use of different wrapping materials and peg materials. DESIGN:Retrospective observational case series. PARTICIPANTS...

journal_title：Ophthalmology

authors： Yoon JS,Lew H,Kim SJ,Lee SY

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of the Artisan/Verisyse phakic intraocular lens (IOL) for the correction of high myopia. DESIGN:Prospective, open-label, noncomparative, multicenter clinical trial. PARTICIPANTS:A total of 684 adults with axial myopia from -4.5 diopters (D) to -22 D were enrolled: 662 in th...

journal_title：Ophthalmology

authors： Stulting RD,John ME,Maloney RK,Assil KK,Arrowsmith PN,Thompson VM,U.S. Verisyse Study Group.

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To examine phenotypes of age-related macular degeneration (AMD) patients with the complement factor H (CFH) variant (Y402H, C allele at rs1061170). DESIGN:Clinic-based case series study. PARTICIPANTS:The data set contained a total of 956 unrelated cases of AMD. METHODS:Age-related macular degeneration phen...

journal_title：Ophthalmology

authors： Shuler RK Jr,Schmidt S,Gallins P,Hauser MA,Scott WK,Caldwell J,Agarwal A,Haines JL,Pericak-Vance MA,Postel EA

更新日期：2008-03-01 00:00:00

abstract：TOPIC:The incidence and morbidity of herpes zoster (HZ) and HZ ophthalmicus (HZO), and the potential impact of varicella vaccine on their epidemiology. CLINICAL RELEVANCE:Herpes zoster affects 20% to 30% of the population at some point in their lifetime; approximately 10% to 20% of these individuals will have HZO. ME...

journal_title：Ophthalmology

authors： Liesegang TJ

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:To examine whether glaucoma status or measures of visual function affected by glaucoma are associated with self-reported difficulty with vision-intensive tasks in a population-based study. DESIGN:Cross-sectional study. PARTICIPANTS:One thousand one hundred sixty individuals who participated in the fourth roun...

journal_title：Ophthalmology

authors： Freeman EE,Muñoz B,West SK,Jampel HD,Friedman DS

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:To investigate systematically the natural history of visual outcome in nonarteritic anterior ischemic optic neuropathy (NAION). DESIGN:Cohort study. PARTICIPANTS:Three hundred forty consecutive untreated patients (386 eyes) with NAION, first seen in our clinic from 1973 to 2000. METHODS:At first visit, all...

journal_title：Ophthalmology

authors： Hayreh SS,Zimmerman MB

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:To evaluate the clinical and histopathologic characteristics of Merkel cell carcinoma (MCC) of the eyelid. DESIGN:Retrospective case series and literature review. PARTICIPANTS:Three consecutive patients with MCC of the eyelid who were referred to the Ocular Oncology Unit of Leiden University Medical Center, N...

journal_title：Ophthalmology

authors： Missotten GS,de Wolff-Rouendaal D,de Keizer RJ

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To determine the incidence of central serous chorioretinopathy (CSC) in Olmsted County, Minnesota from 1980 to 2002, determine the associated risk factors for CSC based on previously reported risk factors, investigate for any new risk factors not previously reported, and determine a population-based recurrence ...

journal_title：Ophthalmology

authors： Kitzmann AS,Pulido JS,Diehl NN,Hodge DO,Burke JP

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To report the prevalence of retinal detachment (RD) and results of prophylaxis against detachment from a giant retinal tear in a large cohort of patients with type 1 Stickler syndrome. DESIGN:Retrospective study. PARTICIPANTS:Two hundred four type 1 Stickler syndrome patients. METHOD:Pedigrees and individual...

journal_title：Ophthalmology

authors： Ang A,Poulson AV,Goodburn SF,Richards AJ,Scott JD,Snead MP

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To compare the effect of bimatoprost and the fixed combination of latanoprost and timolol (LTFC) on 24-hour mean intraocular pressure (IOP) after patients are switched from a nonfixed combination of latanoprost and timolol. DESIGN:Randomized, double-masked, multicenter clinical trial. PARTICIPANTS:Two hundr...

journal_title：Ophthalmology

authors： Rossetti L,Karabatsas CH,Topouzis F,Vetrugno M,Centofanti M,Boehm A,Viswanathan A,Vorwerk C,Goldblum D

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:Quantification of diplopia is important for describing severity of strabismus, measuring change over time, and reporting surgical outcomes. The cervical range of motion (CROM) method has been proposed as a simple, inexpensive alternative to the Goldmann perimeter for quantifying diplopia. The purpose of this st...

journal_title：Ophthalmology

authors： Hatt SR,Leske DA,Holmes JM

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:To study the characteristics of nonarteritic anterior ischemic optic neuropathy (NAION) as measured with optical coherence tomography (OCT) at diagnosis and during the first year after the episode. DESIGN:Cohort study. PARTICIPANTS:Twenty-seven patients diagnosed with NAION in our center between April 1, 2004...

journal_title：Ophthalmology

authors： Contreras I,Noval S,Rebolleda G,Muñoz-Negrete FJ

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To measure accuracy and reliability of the computer-based Retinal Image Multiscale Analysis (RISA) system compared with those of recognized retinopathy of prematurity (ROP) experts, for plus disease diagnosis. DESIGN:Evaluation of diagnostic test or technology. PARTICIPANTS:Eleven recognized ROP experts and...

journal_title：Ophthalmology

authors： Koreen S,Gelman R,Martinez-Perez ME,Jiang L,Berrocal AM,Hess DJ,Flynn JT,Chiang MF

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:The presence of retinal nerve fiber layer (RNFL) split bundles recently was described in normal eyes scanned using scanning laser polarimetry. In this study, the authors set out to ascertain whether RNFL split bundles can be found in histologic sections of normal human eyes. DESIGN:Histologic study of postmort...

journal_title：Ophthalmology

authors： Kaliner E,Cohen MJ,Miron H,Kogan M,Blumenthal EZ

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:To evaluate the diagnostic capability of optical coherence tomography (Stratus OCT 3) for early glaucoma in Asian Indian eyes. DESIGN:Cross-sectional observational study. PARTICIPANTS:Two groups of patients (early glaucoma and normal) who satisfied the inclusion and exclusion criteria were included. Early gla...

journal_title：Ophthalmology

authors： Parikh RS,Parikh S,Sekhar GC,Kumar RS,Prabakaran S,Babu JG,Thomas R

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:To determine the prevalence and impact on vision and visual function of ocular comorbidities in a rural Chinese cataract surgical program, and to devise strategies to reduce their associated burden. DESIGN:Cross-sectional cohort study. PARTICIPANTS:Persons undergoing cataract surgery by one of two recently tr...

journal_title：Ophthalmology

authors： Liu Y,Congdon NG,Fan H,Zhao X,Choi K,Lam DS

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:To assess perifoveal capillary blood flow velocity (BFV), capillary occlusion, and retinal thickness at the central fovea in diabetic patients with or without clinically significant macular edema; to examine the relationships of these variables with visual acuity (VA); and to identify their contributions to vis...

journal_title：Ophthalmology

authors： Sakata K,Funatsu H,Harino S,Noma H,Hori S

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:To evaluate selected functional and physical properties of 2 models of accommodative intraocular lenses (IOLs) compared with those of a standard monofocal IOL. DESIGN:Prospective randomized comparative trial. PARTICIPANTS:Subjects were divided into 3 groups. In group 1, 30 eyes (19 subjects) received 1CU IOL ...

journal_title：Ophthalmology

authors： Marchini G,Mora P,Pedrotti E,Manzotti F,Aldigeri R,Gandolfi SA

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:Visual acuity (VA) is the primary outcome measure in many studies involving eye diseases. A standard statistical approach for comparing a continuous measurement such as a VA letter score between 2 treatment groups is to perform a t test comparing the means. However, frequently a binary variable is created from ...

journal_title：Ophthalmology

authors： Beck RW,Maguire MG,Bressler NM,Glassman AR,Lindblad AS,Ferris FL

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To evaluate published literature to assess whether central corneal thickness (CCT) is a risk factor for the presence, development, or progression of glaucomatous optic nerve damage related to primary open-angle glaucoma (POAG). METHODS:A PubMed literature search limited to English language articles conducted...

journal_title：Ophthalmology

authors： Dueker DK,Singh K,Lin SC,Fechtner RD,Minckler DS,Samples JR,Schuman JS

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To determine the cost-effectiveness of cataract surgery worldwide and to compare it with the cost-effectiveness of comparable medical interventions. DESIGN:Meta-analysis. PARTICIPANTS:Approximately 12,000 eyes in the studies selected. METHODS:Articles were identified by searching the literature using the p...

journal_title：Ophthalmology

authors： Lansingh VC,Carter MJ,Martens M

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To evaluate the short-term safety and efficacy of intravitreal bevacizumab for the treatment of cystoid macular edema (CME) secondary to uveitis. DESIGN:Retrospective, noncomparative, interventional case series. PARTICIPANTS:Thirteen patients undergoing treatment for recalcitrant uveitic macular edema at one ...

journal_title：Ophthalmology

authors： Cordero Coma M,Sobrin L,Onal S,Christen W,Foster CS

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To describe the histopathologic features of Descemet's membrane (DM) obtained from Fuchs' endothelial corneal dystrophy (FECD) corneas undergoing Descemet's stripping with endothelial keratoplasty (DSEK) and to assess the presence of advanced glycation end products (AGEs) and their receptors in FECD endothelium...

journal_title：Ophthalmology

authors： Wang Z,Handa JT,Green WR,Stark WJ,Weinberg RS,Jun AS

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To investigate the multifocal electroretinogram (mfERG) in myopic children in relation to the rate of myopia progression. DESIGN:Observational study. PARTICIPANTS:Eighty-one school children with myopia. METHODS:Cycloplegic refraction, ocular biometry, and mfERG recordings were performed in myopic children ...

journal_title：Ophthalmology

authors： Luu CD,Foulds WS,Tan DT

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To develop a new foveal hypoplasia grading system using optical coherence tomography (OCT) and to determine the correlations of visual acuity to the iris transillumination, macular transparency, and foveal hypoplasia grades, respectively, in young albinism patients. DESIGN:Observational case series. PARTICIPA...

journal_title：Ophthalmology

authors： Seo JH,Yu YS,Kim JH,Choung HK,Heo JW,Kim SJ

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To assess agreement between rotating Scheimpflug camera and ultrasound pachymetry in measuring graft central thickness, and compare reproducibility/repeatability of these methods in corneal grafts and normal corneas. DESIGN:Experimental study. PARTICIPANTS:Sixty-five patients with corneal grafts after penetra...

journal_title：Ophthalmology

authors： de Sanctis U,Missolungi A,Mutani B,Grignolo FM

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To determine the association between complement factor H (CFH) polymorphism T1277C (tyrosine-402 --> histidine-402) and phenotypic variations of age-related macular degeneration (AMD). DESIGN:Cross-sectional observational study. PARTICIPANTS:Subjects with dry or wet AMD and a control population consisting of ...

journal_title：Ophthalmology

authors： Narayanan R,Butani V,Boyer DS,Atilano SR,Resende GP,Kim DS,Chakrabarti S,Kuppermann BD,Khatibi N,Chwa M,Nesburn AB,Kenney MC

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:To assess the relationship between cardiovascular disease and cardiovascular risk factors, other than smoking, and risk of long-term incident age-related macular degeneration (AMD). DESIGN:Population-based cohort study. PARTICIPANTS:There were 3654 baseline (1992-1994) participants aged > or = 49 years includ...

journal_title：Ophthalmology

authors： Tan JS,Mitchell P,Smith W,Wang JJ

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To evaluate structural changes in the cornea and anterior chamber (AC) after LASIK for myopia. DESIGN:Retrospective nonrandomized study. PARTICIPANTS:One hundred sixty-one eyes of 83 patients (mean age, 34.5+/-8.3 years) who underwent uneventful LASIK for myopia and myopic astigmatism. The preoperative refrac...

journal_title：Ophthalmology

authors： Nishimura R,Negishi K,Saiki M,Arai H,Shimizu S,Toda I,Tsubota K

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of phototherapeutic keratectomy (PTK) for treatment of striae in LASIK flaps. DESIGN:Retrospective consecutive series. PARTICIPANTS:Forty-seven eyes of 44 patients with flap striae after LASIK with reduced best-corrected visual acuity (VA) or visual symptoms with at least...

journal_title：Ophthalmology

authors： Ashrafzadeh A,Steinert RF

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To determine the increase in isopter extent, resulting from the measurement of, and correction for, individual reaction time (RT; the latency between stimulus presentation and individual patient response), derived under the standardized conditions of semi-automated kinetic perimetry (SKP), and to model the age-...

journal_title：Ophthalmology

authors： Vonthein R,Rauscher S,Paetzold J,Nowomiejska K,Krapp E,Hermann A,Sadowski B,Chaumette C,Wild JM,Schiefer U

更新日期：2007-06-01 00:00:00